High levels of protection induced by a 40-mer synthetic peptide vaccine against the intestinal nematode parasite Trichinella spiralis.

@article{Robinson1995HighLO,
  title={High levels of protection induced by a 40-mer synthetic peptide vaccine against the intestinal nematode parasite Trichinella spiralis.},
  author={Karen C Robinson and Trevor Bellaby and Wing Chung Chan and Derek R. Wakelin},
  journal={Immunology},
  year={1995},
  volume={86 4},
  pages={495-8}
}
Parenteral vaccination, using a 40-mer synthetic peptide from a 43,000 MW immunodominant glycoprotein secreted by the intestinal nematode parasite Trichinella spiralis, induced high levels of protection against a subsequent challenge infection in mice. The expulsion of adult worms from the gut was accelerated following vaccination with peptide 40-80, but peptides 81-120 and 121-160 were not protective. Mesenteric lymph node cells taken from T. spiralis-infected mice showed some proliferation in… CONTINUE READING
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