High levels of circulating endothelial microparticles in patients with acute coronary syndromes.

@article{BernalMizrachi2003HighLO,
  title={High levels of circulating endothelial microparticles in patients with acute coronary syndromes.},
  author={Leon Bernal-Mizrachi and Wenche Jy and Joaquin J Jimenez and J F Soriano Pastor and Lucia M. Mauro and Lawrence L. Horstman and Eduardo J de Marchena and Yeon Soong Ahn},
  journal={American heart journal},
  year={2003},
  volume={145 6},
  pages={962-70}
}
BACKGROUND Endothelial injury plays a critical role in coronary artery disease (CAD), but the assessment of this injury has been problematical. Recently, it has been shown in vitro that endothelial cells (ECs) release endothelial microparticles (EMPs) on activation or apoptosis and that an assay of EMPs can provide useful information on EC status in patients with thrombotic disorders. This study is aimed at assessing possible correlations between EMPs, which are markers of endothelial injury… CONTINUE READING