High levels of IgG4 to Schistosoma mansoni egg antigens in individuals with periportal fibrosis.

@article{Silveira2002HighLO,
  title={High levels of IgG4 to Schistosoma mansoni egg antigens in individuals with periportal fibrosis.},
  author={Alda Maria Soares da Silveira and Jeffrey Bethony and Andr{\'e}a Gazzinelli and Helmut Kloos and L{\'u}cia Alves de Oliveira Fraga and Maria Carolina Barbosa {\'A}lvares and Alu{\'i}zio Rosa Prata and Henrique Leonardo Guerra and Philip T. Loverde and Rodrigo Corr{\^e}a-Oliveira and Giovanni Gazzinelli},
  journal={The American journal of tropical medicine and hygiene},
  year={2002},
  volume={66 5},
  pages={542-9}
}
Specific IgG4 and IgE responses to adult worm antigen and soluble egg antigen (SEA) were examined in 267 individuals from an area in which schistosomiasis mansoni is endemic. Based on information obtained from clinical and sonographic examinations of this sample, the individuals were divided in three groups: 1) 204 individuals without periportal fibrosis, and liver and spleen enlargements; 2) 41 individuals without periportal fibrosis, but presenting with organopathy, with or without… CONTINUE READING

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