High levels of HPV-16 DNA are associated with high-grade cervical lesions in women at risk or infected with HIV.

@article{Fontaine2005HighLO,
  title={High levels of HPV-16 DNA are associated with high-grade cervical lesions in women at risk or infected with HIV.},
  author={Julie Fontaine and Catherine Hankins and M H Mayrand and Jonas Lef{\`e}vre and Deborah Money and Simon Gagnon and Anita Rochelle Rachlis and Karina Pourreaux and Alex S Ferenczy and François Coutl{\'e}e},
  journal={AIDS},
  year={2005},
  volume={19 8},
  pages={785-94}
}
OBJECTIVE To examine associations between levels of episomal and integrated human papillomavirus (HPV) 16 DNA and the grade of cervical disease. DESIGN Cross-sectional data were obtained from a cohort of women with and without HIV infection and with high-risk sexual behaviour. METHODS Episomal and integrated HPV-16 DNA loads were measured in cervicovaginal lavages collected from 75 women (58 HIV seropositive, 17 HIV seronegative) using real-time polymerase chain reaction assays, controlling… CONTINUE READING

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