High level of soluble HLA-G in amniotic fluid is correlated with congenital transmission of Toxoplasma gondii.

@article{RobertGangneux2011HighLO,
  title={High level of soluble HLA-G in amniotic fluid is correlated with congenital transmission of Toxoplasma gondii.},
  author={Florence Robert-Gangneux and Jean-pierre Gangneux and Nicolas Vu and Sylvie Jaillard and Claude Guiguen and Laurence Amiot},
  journal={Clinical immunology},
  year={2011},
  volume={138 2},
  pages={129-34}
}
The expression of human leukocyte antigen (HLA)-G on cytotrophoblast cells contributes to maternal-fetal tolerance. Soluble forms of HLA-G (sHLA-G) can be detected in amniotic fluid (AF) and a decrease of sHLA-G is known to be correlated to fetal loss. In this work we investigated the role of sHLA-G in the transplacental passage of the protozoan parasite… CONTINUE READING