High level of alphafetoprotein (AFP) and persistence of hemopoiesis in the liver of nude mice.

Abstract

Using indirect immunofluorescence, radial immunodiffusion and radioimmunoassay methods, changes in the number of AFP-synthesizing cells in the liver and in the serum AFP concentration during postnatal development were studied in C3H/HeSto and BALB/cLacSto mice (normal and nu/nu (nude) mutants). From the age of 2 weeks, serum AFP levels were significantly… (More)

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