High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy.

@article{Bobbert2012HighLA,
  title={High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy.},
  author={Peter Bobbert and Alexander Jenke and Thomas Bobbert and Uwe K{\"u}hl and Ursula Rauch and Dirk Lassner and Carmen Scheibenbogen and Wolfgang Ch. Poller and Heinz-Peter Schultheiss and Carsten Skurk},
  journal={European journal of heart failure},
  year={2012},
  volume={14 11},
  pages={1265-75}
}
AIM The expression of leptin and resistin is known to be positively correlated with the incidence of chronic heart failure (CHF). Both adipokines have been implicated in immunomodulation and cardiac remodelling. Therefore, we performed for the first time a clinical study to elucidate the effects of leptin and resistin on progression of CHF in patients with non-ischaemic dilated (DCM) and inflammatory (DCMi) cardiomyopathy. METHODS AND RESULTS For the clinical study 120 patients were divided… CONTINUE READING

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