High-intensity focused ultrasound ablation: effective and safe therapy for solid tumors in difficult locations.

@article{Orsi2010HighintensityFU,
  title={High-intensity focused ultrasound ablation: effective and safe therapy for solid tumors in difficult locations.},
  author={Franco Orsi and Lian Zhang and Paolo Arnone and Gianluigi Orgera and Guido Bonomo and Paolo Della Vigna and Lorenzo Monfardini and Kunn Zhou and Wen-zhi Chen and Zhibiao Wang and Umberto Veronesi},
  journal={AJR. American journal of roentgenology},
  year={2010},
  volume={195 3},
  pages={
          W245-52
        }
}
OBJECTIVE The aim of this study was to evaluate the safety and efficacy of ultrasound-guided high-intensity focused ultrasound therapeutic ablation of solid tumors in difficult locations. SUBJECTS AND METHODS A procedure was performed with a focused ultrasound tumor therapeutic system which provides real-time ultrasound guidance. All patients underwent MDCT or MRI, and some patients underwent PET/CT. From November 2007 through April 2009, 31 patients with 38 lesions of the liver and pancreas… 

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TLDR
The authors conclude that high-intensity focused ultrasound ablation is safe and feasible in the treatment of advanced pancreatic cancer.

Ultrasound-Guided High-Intensity Focused Ultrasound (USgHIFU) Ablation in Pancreatic Metastasis from Renal Cell Carcinoma

TLDR
After HIFU ablation, tumor necrosis and reduction in size was achieved without any procedure related complications and there was no evidence of recurrence in the 9-month follow-up, a promising result of USgHIFU, which seems to be safe and effective for the midterm control of the nonresponsive to chemotherapy renal cell carcinoma metastatic disease.

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