High intensity exercise increases expression of matrix metalloproteinases in fast skeletal muscle fibres.

@article{Carmeli2005HighIE,
  title={High intensity exercise increases expression of matrix metalloproteinases in fast skeletal muscle fibres.},
  author={Eli Carmeli and Miri Moas and Shannon L. Lennon and Scott K. Powers},
  journal={Experimental physiology},
  year={2005},
  volume={90 4},
  pages={613-9}
}
Metalloproteinases (MMPs) are proteolytic enzymes that function in the extracellular matrix to degrade connective tissues. While it is clear that exercise-induced injury in skeletal muscle promotes increased expression of MMPs, the relationship between exercise intensity and expression of MMPs in muscles is unknown. These experiments tested the hypothesis that exercise-induced expression of matrix metalloproteinases (MMP-2 and MMP-9) is dose-dependent such that high-intensity endurance exercise… CONTINUE READING
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