High incidence of thyroiditis and anti-thyroid autoantibodies in NOD mice.

@article{Bernard1992HighIO,
  title={High incidence of thyroiditis and anti-thyroid autoantibodies in NOD mice.},
  author={Nicole F Bernard and F Ertug and Howard C. Margolese},
  journal={Diabetes},
  year={1992},
  volume={41 1},
  pages={
          40-6
        }
}
NOD mice develop spontaneous insulin-dependent diabetes mellitus (IDDM) associated with infiltration of pancreatic islets with mononuclear cells. Islet infiltration results in autoimmune destruction of insulin-secreting beta-cells. Because in humans and BB rats diabetes is often associated with autoimmune thyroid disease (ATD), the NOD mouse model was examined for evidence of thyroiditis and serum antibodies reactive with mouse thyroid membrane antigens (MTMAs). The incidence of thyroiditis was… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

Similar Papers

Loading similar papers…