High incidence of serious side effects of high-dose dexamethasone treatment in patients with epidural spinal cord compression


Twenty-eight consecutive patients were given high-dose dexamethasone (96 mg i.v. loading dose, decreasing doses to zero in 14 days) and radiotherapy for epidural spinal cord compression due to malignant disease. There were eight events classified as side effects of the dexamethasone treatment. Four of these were considered as serious (one fatal ulcer with… (More)
DOI: 10.1007/BF00172664


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