High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers.

@article{Halmos2000HighIO,
  title={High incidence of receptors for luteinizing hormone-releasing hormone (LHRH) and LHRH receptor gene expression in human prostate cancers.},
  author={G{\'a}bor Halmos and Jose M Arencibia and Andrew V Schally and Rodney Davis and David G. Bostwick},
  journal={The Journal of urology},
  year={2000},
  volume={163 2},
  pages={623-9}
}
PURPOSE Agonistic analogs of luteinizing hormone-releasing hormone (LHRH) are widely used for therapy of advanced prostate cancer based upon their ability to suppress testosterone secretion in patients. Various studies also indicate that LHRH analogs might have direct inhibitory effects on prostate tumors mediated by specific LHRH receptors. In this study we investigated the presence and characteristics of receptors for LHRH and their messenger (m) ribonucleic acid (RNA) expression in specimens… CONTINUE READING

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Increased incidence of luteinizing hormone-releasing hormone receptor gene messenger RNA expression in hormone-refractory human prostate cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2001
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