High incidence of malignant pheochromocytoma in a surgical unit. 26 cases out of 100 patients operated from 1971 to 1991.

@article{Proye1992HighIO,
  title={High incidence of malignant pheochromocytoma in a surgical unit. 26 cases out of 100 patients operated from 1971 to 1991.},
  author={Charles A. G. Proye and Michel Vix and A. Goropoulos and P Kerlo and Martine C. Lecomte-Houcke},
  journal={Journal of endocrinological investigation},
  year={1992},
  volume={15 9},
  pages={651-63}
}
In this surgical series of 100 pheochromocytomas (PH), where 91 cases were studied and followed up, the frequency of malignancy appears high (29%) on macroscopic criteria observed at the first operation (25 out 26 cases of malignant PH) or thanks to the occurrence of metastases (1 case out of 26 malignant PH). While some clinical signs are suggestive, there is no excretory profile predictive of malignancy. Isolated or predominant secretion of dopamine is not specific of malignancy event if it… CONTINUE READING