High incidence of cetuximab-related infusion reactions in Tennessee and North Carolina and the association with atopic history.

@article{ONeil2007HighIO,
  title={High incidence of cetuximab-related infusion reactions in Tennessee and North Carolina and the association with atopic history.},
  author={Bert H O'Neil and Robert W. Allen and David Robert Spigel and Thomas E. Stinchcombe and Dominic T. Moore and Jordan D. Berlin and Richard M. Goldberg},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2007},
  volume={25 24},
  pages={3644-8}
}
PURPOSE To confirm the anecdotal observation that patients in North Carolina (NC) and Tennessee (TN) treated with cetuximab experience hypersensitivity reactions (HSR) at a much higher rate than are reported nationally and internationally (<or= 3%). PATIENTS AND METHODS Data from patients treated with cetuximab on clinical trials (n = 88) at three research sites were analyzed for grade 3 or 4 HSR. Additional information was obtained from medical records for patients treated with cetuximab at… CONTINUE READING

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