High incidence of amantadine-resistant influenza AH3 viruses isolated during the 2005-2006 winter season in Nara, Japan.

@article{Yoneda2007HighIO,
  title={High incidence of amantadine-resistant influenza AH3 viruses isolated during the 2005-2006 winter season in Nara, Japan.},
  author={Masaki Yoneda and Yumiko Inoue and Yoshiteru Kitahori},
  journal={Japanese journal of infectious diseases},
  year={2007},
  volume={60 1},
  pages={53-4}
}
We examined the incidence of amantadine-resistant influenza AH3 viruses isolated in Nara Prefecture during the 2005-06 winter season. The genetic analyses of the M2 ion channel protein were conducted using reverse transcriptase PCR and direct sequencing. Thirteen out of 18 (72.2%) strains were identified as amantadine-resistant, and this incidence was remarkably higher than those previously recored in Nara Prefecture. Genetic analyses of the viruses revealed that all the anti-drug strains… CONTINUE READING