High in vitro antimicrobial activity of synthetic antimicrobial peptidomimetics against staphylococcal biofilms.

@article{Flemming2009HighIV,
  title={High in vitro antimicrobial activity of synthetic antimicrobial peptidomimetics against staphylococcal biofilms.},
  author={K. Flemming and C. Klingenberg and J. P. Cavanagh and Merethe Sletteng and W. Stensen and J. Svendsen and T. Flaegstad},
  journal={The Journal of antimicrobial chemotherapy},
  year={2009},
  volume={63 1},
  pages={
          136-45
        }
}
OBJECTIVES The aim of the study was to investigate the antimicrobial effect of different antibiotics and synthetic antimicrobial peptidomimetics (SAMPs) on staphylococcal biofilms. METHODS Biofilms of six staphylococcal strains (two Staphylococcus haemolyticus, two Staphylococcus epidermidis and two Staphylococcus aureus isolates) were grown for 24 h in microtitre plates. They were washed and treated for 24 h with different concentrations of linezolid, tetracycline, rifampicin and vancomycin… Expand
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