High in vitro antimicrobial activity of β-peptoid-peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis.

@article{Liu2013HighIV,
  title={High in vitro antimicrobial activity of β-peptoid-peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis.},
  author={Yang Liu and Kolja M Knapp and Liang Yang and Soeren Molin and Henrik Franzyk and Anders Folkesson},
  journal={International journal of antimicrobial agents},
  year={2013},
  volume={41 1},
  pages={20-7}
}
An array of β-peptoid-peptide hybrid oligomers displaying different amino acid/peptoid compositions and chain lengths was studied with respect to antimicrobial activity against Staphylococcus epidermidis both in planktonic and biofilm cultures, comparing the effects with those of the common antibiotic vancomycin. Susceptibility and time-kill assays were performed to investigate activity against planktonic cells, whilst confocal laser scanning microscopy was used to investigate the dynamics of… CONTINUE READING