High homocysteine, low folate, and low vitamin B6 concentrations: prevalent risk factors for vascular disease in heart transplant recipients.

@article{Gupta1998HighHL,
  title={High homocysteine, low folate, and low vitamin B6 concentrations: prevalent risk factors for vascular disease in heart transplant recipients.},
  author={Ajay Gupta and A. A. Moustapha and Donald Weldon Jacobsen and Marlene Goormastic and Emin Murat Tuzcu and Robert J. Hobbs and James Everett Young and Kathryn James and Peter Mccarthy and Frederick Van Lente and Ralph Green and Killian Robinson},
  journal={Transplantation},
  year={1998},
  volume={65 4},
  pages={
          544-50
        }
}
BACKGROUND A high plasma homocysteine concentration is a risk factor for atherosclerosis and thrombosis, which are major causes of morbidity and mortality in heart transplant patients. High homocysteine concentrations may be caused by lower folate and vitamin B6 levels. We hypothesized that these patients might have high homocysteine concentrations and low levels of folate and vitamin B6, which could contribute to the development of vascular complications. METHODS Total fasting plasma… CONTINUE READING

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