High-grade human brain tumors exhibit increased expression of myelin transcription factor 1 (MYT1), a zinc finger DNA-binding protein.

@article{Armstrong1997HighgradeHB,
  title={High-grade human brain tumors exhibit increased expression of myelin transcription factor 1 (MYT1), a zinc finger DNA-binding protein.},
  author={Regina C Armstrong and Annik Migneault and Mychelle L Shegog and Jae Gon Kim and Lynn D. Hudson and Richard B. Hessler},
  journal={Journal of neuropathology and experimental neurology},
  year={1997},
  volume={56 7},
  pages={772-81}
}
Detection and characterization of distinct central nervous system (CNS) tumor cell types is clinically important since distinct tumor types are associated with different prognoses and treatments. However, there is currently a lack of markers to identify certain glioma types and insufficient understanding as to which cells give rise to different glioma cell types. In the present study, biopsy specimens from human brain tumors were analyzed for expression of Myelin Transcription Factor 1 (MYT1… CONTINUE READING
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