• DOI:10.1007/s11010-016-2828-5
Corpus ID: 16705558

High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress

@article{Balakumar2016HighfructoseDI,
  title={High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress},
  author={M. Balakumar and L. Raji and D. Prabhu and C. Sathishkumar and P. Prabu and V. Mohan and M. Balasubramanyam},
  journal={Molecular and Cellular Biochemistry},
  year={2016},
  volume={423},
  pages={93-104}
}

M. Balakumar, L. Raji, +4 authors M. Balasubramanyam

Published 2016

Biology, Medicine

Molecular and Cellular Biochemistry

In the context of high human consumption of fructose diets, there is an imperative need to understand how dietary fructose intake influence cellular and molecular mechanisms and thereby affect β-cell dysfunction and insulin resistance. While evidence exists for a relationship between high-fat-induced insulin resistance and metabolic disorders, there is lack of studies in relation to high-fructose diet. Therefore, we attempted to study the effect of different diets viz., high-fat diet (HFD… CONTINUE READING

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