High-frequency rTMS treatment increases left prefrontal myo-inositol in young patients with treatment-resistant depression

@article{Zheng2010HighfrequencyRT,
  title={High-frequency rTMS treatment increases left prefrontal myo-inositol in young patients with treatment-resistant depression},
  author={Huirong Zheng and Lei Zhang and Lingjiang Li and Peng Liu and Weiwei Men},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2010},
  volume={34},
  pages={1189-1195}
}
BACKGROUND Neuroimaging studies suggest that the prefrontal cortex (PFC) is involved in the pathophysiology of major depression. Repetitive transcranial magnetic stimulation (rTMS) as an antidepressant intervention has increasingly been investigated in the last two decades. In this study metabolic changes within PFC of severely depressed patients before and after rTMS were evaluated by proton magnetic resonance spectroscopy (1H-MRS). METHOD Thirty-four young depressed patients with treatment… CONTINUE READING
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