High frequency production of hybridomas secreting antibodies to cell antigens.

Abstract

The efficiency of various immunization protocols for the production of hybridomas secreting immunoglobulins specific to cell antigens was evaluated in 15 different fusion experiments. Some of these experiments were performed with splenic B-lymphocytes from mice at different stages of immunization. This approach allowed a dynamic analysis of immunocompetent… (More)

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@article{Cianfriglia1987HighFP, title={High frequency production of hybridomas secreting antibodies to cell antigens.}, author={Maurizio Cianfriglia and Marianna Nuti and Valeria Turchi and Stefano Barca and Marina Tombesi and Stefania Morrone and Carlo Cenciarelli and Pier Giorgio Natali}, journal={Hybridoma}, year={1987}, volume={6 6}, pages={673-7} }