High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer.

@article{Zhang2015HighFO,
  title={High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer.},
  author={Yanling Zhang and X Mao and Xiaoyan Liu and Rong-rong Song and Daniel Berney and Yong-Jie Lu and Guo-ping Ren},
  journal={International journal of clinical and experimental medicine},
  year={2015},
  volume={8 9},
  pages={15127-36}
}
Chromosomal rearrangements and fusion genes play important roles in tumor development and progression. Four high-frequency prostate cancer (CaP) specific fusion genes, SDK1:AMACR, RAD50:PDLIM4, CTAGE5:KHDRBS3 and USP9Y:TTTY15 have been reported in Chinese CaP samples through a transcriptome sequencing study. We previously reported that USP9Y:TTTY15 is a transcription-mediated chimeric RNA, which is expressed in both tumor and non-malignant samples, and here we attempted to confirm the existence… CONTINUE READING