High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F.

@article{Rattner1997HighFO,
  title={High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F.},
  author={J. B. Rattner and John Rees and Clark M. Whitehead and Carlos A Casiano and Eng M Tan and Ren{\'e} Louis Humbel and Karsten Conrad and Marvin J. Fritzler},
  journal={Clinical and investigative medicine. Medecine clinique et experimentale},
  year={1997},
  volume={20 5},
  pages={308-19}
}
OBJECTIVE To study the clinical features of patients with autoantibodies to centromere protein CENP-F and the frequency of CENP-F autoantibodies in patients with various diseases. DESIGN Retrospective clinical and serologic study. METHODS Thirty-six patients with anti-CENP-F were identified by a characteristic pattern of indirect immunofluorescence (IIF) on HEp-2 cells. Fifty patients with melanoma, 50 with breast cancer, 10 with lung cancer, 354 with systemic sclerosis, 120 with systemic… CONTINUE READING
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