High frequency of circulating follicular helper T cells is correlated with B cell subtypes in patients with ankylosing spondylitis.

@article{Long2018HighFO,
  title={High frequency of circulating follicular helper T cells is correlated with B cell subtypes in patients with ankylosing spondylitis.},
  author={Siqi Long and Li Ma and Dongsheng Wang and Xianwen Shang},
  journal={Experimental and therapeutic medicine},
  year={2018},
  volume={15 5},
  pages={
          4578-4586
        }
}
T follicular helper (Tfh) cells are known to support effector B cells and enhance autoimmunity; however, the association between the Tfh cells and B cells in ankylosing spondylitis (AS) is unclear. The aim of the present study was to measure the frequency of circulating cluster of differentiation (CD)4+ C-X-C chemokine receptor type 5 (CXCR5)+ Tfh cells and B cell subtypes in peripheral blood from patients with AS, and evaluate the correlation of these factors. Percentages of peripheral blood… CONTINUE READING

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