High frequency of c-Met expression in gastric cancers producing alpha- fetoprotein.

@article{Amemiya2000HighFO,
  title={High frequency of c-Met expression in gastric cancers producing alpha- fetoprotein.},
  author={Hideki Amemiya and Koji Kono and Yoshiyuki Mori and Akihiro Takahashi and Fumiko Ichihara and Hidehiko Iizuka and Takayoshi Sekikawa and Yoshiro Matsumoto},
  journal={Oncology},
  year={2000},
  volume={59 2},
  pages={145-51}
}
Gastric cancers producing alpha-fetoprotein (AFP) have a poor prognosis and a high incidence of liver metastasis. Hepatocyte growth factor (HGF) and its receptor, c-Met, are known to induce mitosis and cell movement and to promote tumor progression. In the present study, c-Met and HGF expression in AFP-producing gastric cancer was compared with those gastric cancers that do not produce AFP. Twenty-six patients with AFP-producing gastric cancers [AFP(+)] and 26 patients stage-matched gastric… CONTINUE READING

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Alpha-fetoprotein producing gastric cancer.

Journal of the Formosan Medical Association = Taiwan yi zhi • 2016

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