High-frequency, short-latency disinhibition bursting of midbrain dopaminergic neurons.


During reinforcement and sequence learning, dopaminergic neurons fire bursts of action potentials. Dopaminergic neurons in vivo receive strong background excitatory and inhibitory inputs, suggesting that one mechanism by which bursts may be produced is disinhibition. Unfortunately, these inputs are lost during slice preparation and are not precisely… (More)
DOI: 10.1152/jn.01076.2010

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