High-frequency, magnetic-field-responsive drug release from magnetic nanoparticle/organic hybrid based on hyperthermic effect.

@article{Hayashi2010HighfrequencyMD,
  title={High-frequency, magnetic-field-responsive drug release from magnetic nanoparticle/organic hybrid based on hyperthermic effect.},
  author={Koichiro Hayashi and Kenji Ono and Hiromi Suzuki and Makoto Sawada and Makoto Moriya and Wataru Sakamoto and Toshinobu Yogo},
  journal={ACS applied materials & interfaces},
  year={2010},
  volume={2 7},
  pages={1903-11}
}
Magnetic nanoparticles (MNPs) generate heat when a high-frequency magnetic field (HFMF) is applied to them. Induction heat is useful not only for hyperthermia treatment but also as a driving force for drug-release. beta-Cyclodextrin (CD) can act as drug container because of its inclusion properties. Drugs incorporated in the CD can thus be released through the use of induction heating, or hyperthermic effects, by applying a HFMF. In this study, we have synthesized folic acid (FA) and CD… CONTINUE READING

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