High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis

@article{Lin2019HighflowNC,
  title={High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis},
  author={Jilei Lin and Yin Zhang and Limei Xiong and Sha Liu and Cai-hui Gong and Jihong Dai},
  journal={Archives of Disease in Childhood},
  year={2019},
  volume={104},
  pages={564 - 576}
}
Objectives To review the effects and safety of high-flow nasal cannula (HFNC) for bronchiolitis. Methods Six electronic databases including PubMed, EMBASE, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, CQ VIP Database and Wanfang Data were searched from their inception to 1 June 2018. Randomised controlled trials (RCTs) which investigated the effects of HFNC versus other forms of oxygen therapies for bronchiolitis were included. Results Nine RCTs with… 

Efficacy and safety of high flow nasal oxygen for children with bronchiolitis: systematic review and meta-analysis

HFNC is superior to SOT in terms of treatment failure and there is no significant difference between HFNC and CPAP in termsof treatment failure, which suggest HFNC is safe to use in acute hospital settings.

High‐flow oxygen in bronchiolitis

  • Medicine
    Journal of paediatrics and child health
  • 2019
High-flow nasal cannula oxygen is less invasive than CPAP and can be a useful intervention for babies who need more than standard oxygen treatment but do not yet need CPAP or more invasive ventilation.

High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot.

In this pilot study, treatment with HFNC resulted in a rate of treatment failure similar to CPAP, and Pediatric intensive care unit length of stay was similar between the CPAP and HFNC groups.

The nutritional impact of a feeding protocol for infants on high flow nasal cannula therapy.

The use of a feeding protocol for patients with bronchiolitis on HFNC was safe and associated with shorter time to initiate EN and shorter length of hospital stay.

Outcomes of High-Flow Nasal Cannula Vs. Nasal Continuous Positive Airway Pressure in Young Children With Respiratory Distress: A Systematic Review and Meta-Analysis

Among children with respiratory distress younger than 2 years, HFNC appears to be associated with higher risk of treatment failure and possibly, an increased risk of need for intubation and mortality.

High-flow nasal cannula oxygen therapy in children: a clinical review

  • J. Kwon
  • Medicine
    Clinical and experimental pediatrics
  • 2020
The development of clinical guidelines for HFNC, including flow settings, indications, and contraindications, device management, efficacy identification, and safety issues are needed, particularly in children.

Acceptability of Deimplementing High-Flow Nasal Cannula in Pediatric Bronchiolitis.

Deimplementation of HFNC in children with bronchiolitis is acceptable among providers and hospital leaders should educate staff, create a culture for safely doing less, and enhance multidisciplinary communication to facilitate deimplementation.
...

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Objective To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis.

High flow therapy versus hypertonic saline in bronchiolitis: randomised controlled trial

Objective To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis.

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The efficacy and security of HHFNC on moderate and severe bronchiolitis are better than those of nCPAP, and it is recommended for clinical application widely.

High-flow nasal cannula therapy for infants with bronchiolitis.

The current evidence is of low quality, from one small study with uncertainty about the estimates of effect and an unclear risk of performance and detection bias, and the included study provides some indication that HFNC therapy is feasible and well tolerated.

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Among infants with bronchiolitis who were treated outside an ICU, those who received high‐flow oxygen therapy had significantly lower rates of escalation of care due to treatment failure than those in the group that received standard oxygen therapy.

Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery

HFNP therapy has dramatically changed ventilatory practice in infants <24 months of age in this institution, and appears to reduce the need for intubation in infants with viral bronchiolitis.

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CPAP was more effective than HFNC in decreasing respiratory rate (RR) and FiO2 and no differences were observed in length of treatment or complications.

Nasopharyngeal Airway Pressures in Bronchiolitis Patients Treated With High-Flow Nasal Cannula Oxygen Therapy

Increasing flow rates of HHHFNC therapy are associated with linear increases in NP pressures in bronchiolitis patients, and only flow (not weight or gender) had an effect on generated pressure.

High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study)

In young infants with moderate to severe AVB, initial management with HFNC did not have a failure rate similar to that of nCPAP, and the success rate with the alternative respiratory support, intubation rate, durations of noninvasive and invasive ventilation, skin lesions, and length of PICU stay were comparable between groups.

Improved clinical and economic outcomes in severe bronchiolitis with pre-emptive nCPAP ventilatory strategy

PurposeSevere bronchiolitis is the leading cause of admission to the pediatric intensive care unit (PICU). Nasal continuous positive airway pressure (nCPAP) has become the primary respiratory