High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis
@article{Lin2019HighflowNC, title={High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis}, author={Jilei Lin and Yin Zhang and Limei Xiong and Sha Liu and Cai-hui Gong and Jihong Dai}, journal={Archives of Disease in Childhood}, year={2019}, volume={104}, pages={564 - 576} }
Objectives To review the effects and safety of high-flow nasal cannula (HFNC) for bronchiolitis. Methods Six electronic databases including PubMed, EMBASE, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, CQ VIP Database and Wanfang Data were searched from their inception to 1 June 2018. Randomised controlled trials (RCTs) which investigated the effects of HFNC versus other forms of oxygen therapies for bronchiolitis were included. Results Nine RCTs with…
67 Citations
The Effects and Safety of Continuous Positive Airway Pressure in Children with Bronchiolitis: A Systematic Review and Meta-Analysis.
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CPAP for the initial respiratory management significantly benefit children with bronchiolitis, the delivery of CPAP by helmet may be a better choice, and more high-quality research is needed to confirm the conclusion.
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HFNC is superior to SOT in terms of treatment failure and there is no significant difference between HFNC and CPAP in termsof treatment failure, which suggest HFNC is safe to use in acute hospital settings.
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Experimental evidence does not suggest that high-flow oxygen therapy has advantages over LFOT as initial treatment nor over NIV as a rescue treatment, and the included studies show methodological heterogeneity, but it is only statistically significant for the reduction of days of oxygen therapy and length of hospital stay.
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Continuous Positive Airway Pressure vs. High Flow Nasal Cannula in children with acute severe or moderate bronchiolitis. A systematic review and Meta-analysis.
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High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot.
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- 2020
In this pilot study, treatment with HFNC resulted in a rate of treatment failure similar to CPAP, and Pediatric intensive care unit length of stay was similar between the CPAP and HFNC groups.
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- 2022
The use of a feeding protocol for patients with bronchiolitis on HFNC was safe and associated with shorter time to initiate EN and shorter length of hospital stay.
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Among children with respiratory distress younger than 2 years, HFNC appears to be associated with higher risk of treatment failure and possibly, an increased risk of need for intubation and mortality.
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