High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis

@article{Lin2019HighflowNC,
  title={High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis},
  author={Jilei Lin and Yin Zhang and Limei Xiong and Sha Liu and Cai-hui Gong and Jihong Dai},
  journal={Archives of Disease in Childhood},
  year={2019},
  volume={104},
  pages={564 - 576}
}
Objectives To review the effects and safety of high-flow nasal cannula (HFNC) for bronchiolitis. Methods Six electronic databases including PubMed, EMBASE, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, CQ VIP Database and Wanfang Data were searched from their inception to 1 June 2018. Randomised controlled trials (RCTs) which investigated the effects of HFNC versus other forms of oxygen therapies for bronchiolitis were included. Results Nine RCTs with… 
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62 Citations
Highly Influential Citations
1
Background Citations
8
Methods Citations
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62 Citations

Efficacy and safety of high flow nasal oxygen for children with bronchiolitis: systematic review and meta-analysis

HFNC is superior to SOT in terms of treatment failure and there is no significant difference between HFNC and CPAP in termsof treatment failure, which suggest HFNC is safe to use in acute hospital settings.

High‐flow oxygen in bronchiolitis

  • Medicine
    Journal of paediatrics and child health
  • 2019
High-flow nasal cannula oxygen is less invasive than CPAP and can be a useful intervention for babies who need more than standard oxygen treatment but do not yet need CPAP or more invasive ventilation.

Continuous Positive Airway Pressure vs. High Flow Nasal Cannula in children with acute severe or moderate bronchiolitis. A systematic review and Meta-analysis.

Continuous Positive Airway Pressure vs. High Flow Nasal Cannula in children with acute severe or moderate bronchiolitis. A systematic review and Meta-analysis.

High-Flow Nasal Cannula versus Continuous Positive Airway Pressure in Critical Bronchiolitis: A Randomized Controlled Pilot.

In this pilot study, treatment with HFNC resulted in a rate of treatment failure similar to CPAP, and Pediatric intensive care unit length of stay was similar between the CPAP and HFNC groups.

The nutritional impact of a feeding protocol for infants on high flow nasal cannula therapy.

The use of a feeding protocol for patients with bronchiolitis on HFNC was safe and associated with shorter time to initiate EN and shorter length of hospital stay.

Outcomes of High-Flow Nasal Cannula Vs. Nasal Continuous Positive Airway Pressure in Young Children With Respiratory Distress: A Systematic Review and Meta-Analysis

Among children with respiratory distress younger than 2 years, HFNC appears to be associated with higher risk of treatment failure and possibly, an increased risk of need for intubation and mortality.

Clinical factors associated with intubation in the high flow nasal cannula era.

High-flow nasal cannula oxygen therapy in children: a clinical review

  • J. Kwon
  • Medicine
    Clinical and experimental pediatrics
  • 2020
The development of clinical guidelines for HFNC, including flow settings, indications, and contraindications, device management, efficacy identification, and safety issues are needed, particularly in children.

Acceptability of Deimplementing High-Flow Nasal Cannula in Pediatric Bronchiolitis.

Deimplementation of HFNC in children with bronchiolitis is acceptable among providers and hospital leaders should educate staff, create a culture for safely doing less, and enhance multidisciplinary communication to facilitate deimplementation.
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References

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Objective To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis.…

High flow therapy versus hypertonic saline in bronchiolitis: randomised controlled trial

Objective To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis.…

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The efficacy and security of HHFNC on moderate and severe bronchiolitis are better than those of nCPAP, and it is recommended for clinical application widely.

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HFNP therapy has dramatically changed ventilatory practice in infants <24 months of age in this institution, and appears to reduce the need for intubation in infants with viral bronchiolitis.

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