High-flow nasal cannula: Mechanisms, evidence and recommendations.

  title={High-flow nasal cannula: Mechanisms, evidence and recommendations.},
  author={Brett James Manley and Louise S Owen},
  journal={Seminars in fetal & neonatal medicine},
  volume={21 3},
The use of high-flow nasal cannula (HF) therapy as respiratory support for preterm infants is rapidly increasing, due to its perceived ease of use and other potential benefits over the standard 'non-invasive' respiratory support, continuous positive airway pressure (CPAP). The evidence from randomized trials suggests that HF is an alternative to CPAP for post-extubation support of preterm infants. Limited data are available from randomized trials comparing HF with CPAP as primary support, and… CONTINUE READING