High flexibility of DNA on short length scales probed by atomic force microscopy.

@article{Wiggins2006HighFO,
  title={High flexibility of DNA on short length scales probed by atomic force microscopy.},
  author={Paul A. Wiggins and Thijn van der Heijden and Fernando Moreno-Herrero and Andrew J. Spakowitz and Rob Phillips and Jonathan Widom and Cees Dekker and Philip C. Nelson},
  journal={Nature nanotechnology},
  year={2006},
  volume={1 2},
  pages={137-41}
}
The mechanics of DNA bending on intermediate length scales (5-100 nm) plays a key role in many cellular processes, and is also important in the fabrication of artificial DNA structures, but previous experimental studies of DNA mechanics have focused on longer length scales than these. We use high-resolution atomic force microscopy on individual DNA molecules to obtain a direct measurement of the bending energy function appropriate for scales down to 5 nm. Our measurements imply that the elastic… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.
96 Citations
22 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 96 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

High flexibility of DNA on short length scales probed by atomic force microscopy

  • P. A. Wiggins
  • Nature Nanotechnology
  • 2006

Structural analysis of hyperperiodic DNA from Caenorhabditis elegans

  • F. Moreno-Herrero
  • Nucleic Acids Res
  • 2006

Similar Papers

Loading similar papers…