High feed intake increases liver blood flow and metabolism of progesterone and estradiol-17beta in dairy cattle.

@article{Sangsritavong2002HighFI,
  title={High feed intake increases liver blood flow and metabolism of progesterone and estradiol-17beta in dairy cattle.},
  author={Siwat Sangsritavong and David K. Combs and Roberto Sartori and Louis E. Armentano and Milo C Wiltbank},
  journal={Journal of dairy science},
  year={2002},
  volume={85 11},
  pages={2831-42}
}
Increased liver blood flow (LBF) resulting from elevated feed intake in lactating dairy cows may increase steroid metabolism. Continuous infusion of bromosulphthalein (BSP; specifically metabolized in liver) was used to measure LBF. Similarly, progesterone (P4) and estradiol-17beta (E2) were administered by continuous infusion. Circulating concentrations at steady state were used to calculate the metabolic clearance rate (MCR) of BSP, P4, and E2. Experiment 1: Variation in LBF was determined in… CONTINUE READING
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