High-fat diets impede the lowering effect of cyclosporine a on rat brain lipids and interact with the expression of apolipoproteins E and J

Abstract

Cyclosporine A (CsA), a common immunosuppressive agent, produces hyperlipidemia and apolipoprotein profile alterations in plasma as well as neurological and psychiatric complications. In rats, 10 mg CsA/kg/d treatments for 3 wk induce alterations of the electroencephalogram, and of the blood and brain lipids. Using this model, we evaluated whether… (More)
DOI: 10.1007/s11745-005-1360-x

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@article{Montpied2005HighfatDI, title={High-fat diets impede the lowering effect of cyclosporine a on rat brain lipids and interact with the expression of apolipoproteins E and J}, author={Pascale Montpied and Nicol{\'e} Domingo and Mich{\`e}le Senft and Henri Portugal and Pierre Petit and Françoise Chanussot}, journal={Lipids}, year={2005}, volume={40}, pages={59-67} }