High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo

Abstract

NAFLD (non-alcoholic fatty liver disease), associated with obesity and the cardiometabolic syndrome, is an important medical problem affecting up to 20% of western populations. Evidence indicates that mitochondrial dysfunction plays a critical role in NAFLD initiation and progression to the more serious condition of NASH (non-alcoholic steatohepatitis… (More)
DOI: 10.1042/BJ20080868

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