High fat diet-induced glucose intolerance impairs myocardial function, but not myocardial perfusion during hyperaemia: a pilot study

@inproceedings{Brom2012HighFD,
  title={High fat diet-induced glucose intolerance impairs myocardial function, but not myocardial perfusion during hyperaemia: a pilot study},
  author={Charissa E van den Brom and Carolien S E Bulte and B Margreet Kloeze and Stephan Alexander Loer and Christa Boer and R. Arthur Bouwman},
  booktitle={Cardiovascular diabetology},
  year={2012}
}
BACKGROUND Glucose intolerance is a major health problem and is associated with increased risk of progression to type 2 diabetes mellitus and cardiovascular disease. However, whether glucose intolerance is related to impaired myocardial perfusion is not known. The purpose of the present study was to study the effect of diet-induced glucose intolerance on myocardial function and perfusion during baseline and pharmacological induced hyperaemia. METHODS Male Wistar rats were randomly exposed to… CONTINUE READING