High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan.

@article{Chen2013HighEO,
  title={High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan.},
  author={J Chen and K L Yeh and Yu-min Yang and Jan-Gowth Chang and Huey-Er Lee and Shih-Ya Hung},
  journal={Medical oncology},
  year={2013},
  volume={30 2},
  pages={513}
}
Since 2008, oral squamous cell carcinoma (OSCC) has climbed to the fourth place in cancer mortality in the male population of Taiwan. Epigenetic regulations including DNA methylation and histone modification control gene expression and play important roles during cancer progression. Since the relationship between histone modification and prognosis of OSCC is inconclusive, we collected 215 formalin-fixed and paraffin-embedded tissues from male patients having OSCC and surveyed them by tissue… CONTINUE READING

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