High expression of LMO2 predicts a favorable outcome in adult patients with BCR/ABL negative B-cell acute lymphoblastic leukemia.

@article{Aly2016HighEO,
  title={High expression of LMO2 predicts a favorable outcome in adult patients with BCR/ABL negative B-cell acute lymphoblastic leukemia.},
  author={Rabab Hamed. M. Aly and Mona M. Taalab and Eman M Abdsalam and Omar H Elyamany and Omar Hasan},
  journal={Oncology letters},
  year={2016},
  volume={11 3},
  pages={
          1917-1922
        }
}
The LIM domain only protein 2 (LMO2) is a key regulator of hematopoietic stem cell development. Expression of LMO2 has been evaluated in B-cell lymphoma, T-cell acute lymphoblastic leukemia and acute myeloid leukemia; however, information concerning its role in breakpoint cluster region/Abelson murine leukemia viral oncogene homolog 1 (BCR/ABL) negative B-cell acute lymphoblastic leukemia (B-ALL) remains limited. The present study investigated LMO2 expression using quantitative polymerase chain… CONTINUE READING