High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma

@inproceedings{Ye2015HighEO,
  title={High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma},
  author={Yibiao Ye and Jie Chen and Yu Zhou and Zhiqiang Fu and Quanbo Zhou and Yingxue Wang and Wenchao Gao and Shangyou Zheng and Xiaohui Zhao and Tao Chen and Rufu Chen},
  booktitle={Journal of Translational Medicine},
  year={2015}
}
Pancreatic ductal adenocarcinoma (PDAC) is still a lethal malignancy. Long noncoding RNAs (lncRNAs) have been shown to play a critical role in cancer development and progression. Here we identified overexpression of the lncRNA AFAP1-AS1 in PDAC patients and evaluated its prognostic and functional relevance. The global lncRNA expression profile in PDAC was measured by lncRNA microarray. Expression of AFAP1-AS1 was evaluated by reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR… CONTINUE READING