High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma.

@article{Yang2010HighEL,
  title={High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma.},
  author={Xin-Rong Yang and Yang Xu and Bin Yu and Jian Zhou and Shuang-jian Qiu and Guo-Ming Shi and Boheng Zhang and Wei-zhong Wu and Ying-hong Shi and Bin Wu and Guo-huan Yang and Yuan Ji and Jia Fan},
  journal={Gut},
  year={2010},
  volume={59 7},
  pages={953-62}
}
BACKGROUND/AIMS To investigate the prognostic values of putative hepatic stem/progenitor cell (HSC/HPC) biomarkers in patients with hepatocellular carcinoma (HCC). METHODS Fourteen biomarkers related to HSCs/HPCs or tumour angiogenesis were assessed by qRT-PCR and then validated by tissue microarrays (TMAs) in three independent cohorts of patients with HCC undergoing curative resection (n=67, 314 and 73). RESULTS Most of the biomarkers were found to be overexpressed in patients with… CONTINUE READING