High-energy phosphates and function in isolated, working rabbit hearts.

@article{Lewandowski1987HighenergyPA,
  title={High-energy phosphates and function in isolated, working rabbit hearts.},
  author={E Douglas Lewandowski and Michael D. Devous and Ray L Nunnally},
  journal={The American journal of physiology},
  year={1987},
  volume={253 5 Pt 2},
  pages={H1215-23}
}
An isolated, working, rabbit heart has been developed for use with nuclear magnetic resonance (NMR) spectroscopy. This model is functionally stable over a 4-h period and displays classic hemodynamic responses to work-load changes. Control 31P spectra of this preparation (n = 5) were obtained with simultaneous recordings of left ventricular pressure (LVP), LVP differentiated with respect to time (dP/dt), heart rate (HR), and cardiac output (CO). ATP, phosphocreatine (PCr), and hemodynamics… CONTINUE READING