High endothelial venule-like vessels and lymphocyte recruitment in testicular seminoma.

@article{Sakai2014HighEV,
  title={High endothelial venule-like vessels and lymphocyte recruitment in testicular seminoma.},
  author={Yoshitaka Sakai and Hiroko Hoshino and Riko Kitazawa and Motohiro Kobayashi},
  journal={Andrology},
  year={2014},
  volume={2 2},
  pages={282-9}
}
Seminoma, the most common testicular malignant neoplasm, originates from germ cells and is characterized by the presence of numerous tumour-infiltrating lymphocytes (TILs). Although it is widely accepted that TILs function in surveillance and cytotoxicity in various tumours including seminoma, detailed mechanisms governing TIL recruitment are not fully understood. It has been shown that high endothelial venule (HEV)-like vessels are induced in inflamed and neoplastic tissues and contribute to… CONTINUE READING

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