High efficiency differentiation of human pluripotent stem cells to cardiomyocytes and characterization by flow cytometry.

@article{Bhattacharya2014HighED,
  title={High efficiency differentiation of human pluripotent stem cells to cardiomyocytes and characterization by flow cytometry.},
  author={Subarna Bhattacharya and Paul W. Burridge and Erin M. Kropp and Sandra L. Chuppa and Wai-Meng Kwok and Joseph C Wu and Kenneth R. Boheler and Rebekah L Gundry},
  journal={Journal of visualized experiments : JoVE},
  year={2014},
  volume={91},
  pages={52010}
}
There is an urgent need to develop approaches for repairing the damaged heart, discovering new therapeutic drugs that do not have toxic effects on the heart, and improving strategies to accurately model heart disease. The potential of exploiting human induced pluripotent stem cell (hiPSC) technology to generate cardiac muscle "in a dish" for these applications continues to generate high enthusiasm. In recent years, the ability to efficiently generate cardiomyogenic cells from human pluripotent… CONTINUE READING
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