High-efficiency derivation of human embryonic stem cell lines following pre-implantation genetic diagnosis

Abstract

Pre-implantation genetic diagnosis allows the characterisation of embryos that carry a gene responsible for a severe monogenic disease and to transfer to the mother’s uterus only the unaffected one(s). The genetically affected embryos can be used to establish human embryonic stem cell (hESC) lines. We are currently establishing a cell bank of ESC lines… (More)
DOI: 10.1007/s11626-010-9300-8

Topics

6 Figures and Tables

Cite this paper

@article{Tropel2010HighefficiencyDO, title={High-efficiency derivation of human embryonic stem cell lines following pre-implantation genetic diagnosis}, author={Philippe Tropel and Johana Tournois and Julien C{\^o}me and Christine Varela and C{\'e}line Moutou and Pascal Fragner and Michel Cailleret and Yacine La{\^a}bi and Marc R. Peschanski and St{\'e}phane Viville}, journal={In Vitro Cellular & Developmental Biology - Animal}, year={2010}, volume={46}, pages={376-385} }