High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial.

Abstract

BACKGROUND Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of adjunctive vitamin D on sputum culture conversion are absent. METHODS We undertook a multicentre randomised controlled trial of adjunctive vitamin D in adults with sputum… (More)
DOI: 10.1016/S0140-6736(10)61889-2

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@article{Martineau2011HighdoseVD, title={High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial.}, author={Adrian R. Martineau and Peter Mclean Timms and Graham Henry Bothamley and Yasmeen Hanifa and Kamrul Islam and Alleyna P. Claxton and Geoffrey E. Packe and John C Moore-Gillon and Mathina Darmalingam and Robert N. Davidson and Heather June Milburn and Lucy V. Baker and Richard D. Barker and Nicholas Joel Woodward and T. Venton and Korina E Barnes and Christopher J Mullett and Anna K Coussens and Clare M. Rutterford and Charles A. Mein and Geraint Davies and Robert J Wilkinson and Vladyslav Nikolayevskyy and Francis A. Drobniewski and Sandra Eldridge and Chris Griffiths}, journal={Lancet}, year={2011}, volume={377 9761}, pages={242-50} }