High dose urokinase for restoration of patency of occluded permanent central venous catheters in hemodialysis patients.

@article{Shavit2010HighDU,
  title={High dose urokinase for restoration of patency of occluded permanent central venous catheters in hemodialysis patients.},
  author={Linda Shavit and Meyer D. Lifschitz and Joseph Plaksin and Tal Grenader and Itzchak N Slotki},
  journal={Clinical nephrology},
  year={2010},
  volume={74 4},
  pages={297-302}
}
BACKGROUND Catheter thrombosis is common and results in inadequate dialysis treatment and, frequently, in catheter loss. Since dialysis treatment runs on a strict schedule, occluded catheters need to be restored in a timely and cost effective manner. We present a new shortened protocol of urokinase infusion that allows hemodialysis to be performed within 90 minutes. METHODS To chronic hemodialysis patients, who developed complete catheter occlusion, urokinase was infused simultaneously… CONTINUE READING