High dose rate and flattening filter free irradiation can be safely implemented in clinical practice.


PURPOSE We hypothesize that flattening filter free (FFF) high dose rate irradiation will decrease cell survival in normal and cancer cells with more pronounced effects in DNA repair deficient cells. Additionally, we hypothesize that removal of the flattening filter will result in an enhanced relative biological effectiveness independent of the dose rate… (More)
DOI: 10.3109/09553002.2015.1068457