High dose of primaquine in primaquine resistant vivax malaria.

  title={High dose of primaquine in primaquine resistant vivax malaria.},
  author={Danai Bunnag and Juntra Karbwang and A. Thanavibul and Sunee Chittamas and Y Ratanapongse and Kobsiri Chalermrut and Kesara Na Bangchang and T Harinasuta},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  volume={88 2},
The efficacy of low dose chloroquine, characteristic pattern of relapse and the relapse rate in vivax malaria after high dose primaquine were investigated in 167 Thai patients. 87 patients were allocated at random to receive 300 mg, and 80 received 450 mg of chloroquine on the first day of admission. All patients in both groups showed a rapid response with comparable fever clearance times (27.3 vs. 26.1 h) and parasite clearance times (67.1 vs. 58.1 h). After recovery and clearance of… CONTINUE READING
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