High-dose methylprednisolone sodium succinate as a single agent in relapsed childhood acute lymphoblastic leukaemia.

Abstract

Twenty children received methylprednisolone (1 g/m2), daily for 5 to 8 days, as initial single agent therapy for relapsed acute lymphoblastic leukaemia. Bone marrow blasts were reduced to less than 5% in 2 and 5-10% in 3 of 12 patients with bone marrow relapses. In 3/9 with central nervous system relapses the cerebrospinal fluid (CSF) blasts completely… (More)

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@article{Ryalls1992HighdoseMS, title={High-dose methylprednisolone sodium succinate as a single agent in relapsed childhood acute lymphoblastic leukaemia.}, author={Michael Ryalls and C Ross Pinkerton and S T Meller and Duncan C. S. Talbot and T. J. McElwain}, journal={Medical and pediatric oncology}, year={1992}, volume={20 2}, pages={119-23} }