High-dose melphalan, etoposide, total-body irradiation, and autologous stem-cell reconstitution as consolidation therapy for high-risk Ewing's sarcoma does not improve prognosis.

@article{Meyers2001HighdoseME,
  title={High-dose melphalan, etoposide, total-body irradiation, and autologous stem-cell reconstitution as consolidation therapy for high-risk Ewing's sarcoma does not improve prognosis.},
  author={Paul A Meyers and Mark D. Krailo and Marc Ladanyi and Ka Wah Chan and Scott L. Sailer and Paul S. Dickman and Diana L. Baker and Joseph H. Davis and Robert B. Gerbing and Alfred Grovas and Cynthia E Herzog and Kristina Lindsley and Wen Liu-Mares and James B. Nachman and Lance Sieger and J Wadman and Richard Gorlick},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2001},
  volume={19 11},
  pages={
          2812-20
        }
}
PURPOSE To determine whether consolidation therapy with high-dose melphalan, etoposide, and total-body irradiation (TBI) with autologous stem-cell support would improve the prognosis for patients with newly diagnosed metastatic Ewing's sarcoma (ES). PATIENTS AND METHODS Thirty-two eligible patients with newly diagnosed ES metastatic to bone and/or bone marrow were enrolled onto this study. Treatment was initially comprised of five cycles of induction chemotherapy (cyclophosphamide… CONTINUE READING

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