High-dose indium 111In pentetreotide radiotherapy for metastatic atypical carcinoid tumor.

@article{Meyers2000HighdoseI1,
  title={High-dose indium 111In pentetreotide radiotherapy for metastatic atypical carcinoid tumor.},
  author={Michael O. Meyers and Lowell B. Anthony and Kathleen E. McCarthy and George J. Drouant and T J Maloney and G D Espanan and Eugene A. Woltering},
  journal={Southern medical journal},
  year={2000},
  volume={93 8},
  pages={
          809-11
        }
}
Indium In 111 pentetreotide imaging of neuroendocrine tumors that overexpress somatostatin receptors has become standard for localization of these tumors. This radioligand is internalized into the cell and can induce receptor-specific cytotoxicity by emission of Auger electrons. We hypothesized that high-dose 111In-pentetreotide could be therapeutic in patients with somatostatin receptor-expressing tumors. Our 35-year-old patient had atypical carcinoid tumor metastatic to cervical… CONTINUE READING

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Gastrointestinal neuroendocrine tumors: a role for targeted therapies?

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  • 2007
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